Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198803 | 0.88 | GABRA1 (0.57) | PPARGPPARAPTGS2ALOX5MAPK1 | |
| SCHEMBL9116358 | 0.88 | PPARA (0.71) | PPARGPPARAPTGS2ALOX5ELANE | |
| SCHEMBL11045223 | 0.88 | PPARA (0.71) | PPARGPPARAPTGS2ALOX5ELANE | |
| SCHEMBL11039054 | 0.88 | PPARA (0.71) | PPARGPPARAPTGS2ALOX5ELANE | |
| SCHEMBL29084188 | 0.88 | PPARA (0.71) | PPARGPPARAPTGS2ALOX5ELANE | |
| SCHEMBL5678227 | 0.87 | ALOX5 (0.51) | PPARGPPARAPTGS2ALOX5PRKCI | |
| SCHEMBL5161561 | 0.86 | ALOX5 (0.48) | PPARGPPARAPTGS2ALOX5PRKCI | |
| SCHEMBL4032384 | 0.84 | PTGS2 (0.54) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL11890187 | 0.83 | MAPK1 (0.54) | PPARGPPARAPTGS2ALOX5MAPK1 | |
| SCHEMBL27863247 | 0.81 | THRB (0.60) | PPARGPPARAPTGS2ALOX5PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104341307-B | Phenylacetic acid derivatives and anticancer usage thereof | 北京京朋汇药业研究发展有限公司 | 2016-12-28 | — | — | CN | disclosed |