Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139553 | 0.81 | FGFR1 (0.55) | BACE1P2RX7ALDH1A1MAPTHTT | |
| SCHEMBL27686351 | 0.78 | PDE4B (0.61) | PDE4BBACE1P2RX7CDC25BPTPRC | |
| SCHEMBL15656245 | 0.76 | PDE4B (0.50) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL516326 | 0.75 | PDE4B (0.54) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL6674116 | 0.73 | PTGS2 (0.55) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL4916317 | 0.73 | ALDH1A1 (0.61) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL11619315 | 0.73 | ALDH1A1 (0.61) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL28351836 | 0.73 | ALDH1A1 (0.61) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL20160837 | 0.72 | PDE4B (0.52) | PDE4BBACE1P2RX7ALDH1A1MAPT | |
| SCHEMBL13170491 | 0.72 | PDE4B (0.52) | PDE4BBACE1P2RX7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | claimed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | claimed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | claimed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | claimed |
| EP-3271346-B1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | UNIV NEVADA RENO (US) | 2021-05-05 | — | — | EP | disclosed |
| WO-2016149633-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2016-09-22 | — | — | WO | disclosed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | disclosed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | disclosed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | KRT18, NDUFA1, NDUFA2 | PDE4B 3987/4885BACE1 4216/4885P2RX7 3875/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | PDE4B 4198/4885BACE1 4385/4885P2RX7 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.