Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162095 | 0.81 | EPHX2 (0.39) | EPHX2NR1H4HPGDGAAMAPT | |
| SCHEMBL5162938 | 0.81 | HPGD (0.34) | EPHX2NR1H4HPGDHCRTR2GAA | |
| SCHEMBL5163543 | 0.80 | ALOX5 (0.46) | EPHX2NR1H4HPGDALOX5GAA | |
| SCHEMBL5162590 | 0.79 | L3MBTL1 (0.42) | EPHX2NR1H4HPGDGAAKDM4E | |
| SCHEMBL5163215 | 0.78 | HSP90AA1 (0.37) | HPGD | |
| SCHEMBL5164405 | 0.78 | GAA (0.38) | EPHX2NR1H4HPGDALOX5GAA | |
| Ammonia Solution, Strong SCHEMBL5307556 | 0.78 | L3MBTL1 (0.41) | EPHX2NR1H4HPGDGAAKDM4E | |
| SCHEMBL5164397 | 0.78 | CTSL (0.38) | EPHX2NR1H4HPGDKDM4EP2RX7 | |
| SCHEMBL5165340 | 0.77 | CA12 (0.37) | EPHX2NR1H4HPGDGAAMAPT | |
| SCHEMBL5164364 | 0.77 | GAA (0.36) | EPHX2NR1H4HPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | EPHX2 2475/4885NR1H4 2501/4885HPGD 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.