Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087178 | 0.82 | HPGD (0.48) | CHRM1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16341947 | 0.82 | CHRM1 (0.34) | CHRM1OPRM1OPRD1OGFRL1HPGD | |
| SCHEMBL4046200 | 0.79 | L3MBTL3 (0.33) | CHRM1KMT2AHPGDCHRM2CHRM3 | |
| SCHEMBL27997009 | 0.78 | CTSK (0.35) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4046093 | 0.77 | HRH3 (0.35) | CTSKCHRM1MEN1ALDH1A1MAPT | |
| SCHEMBL31209769 | 0.76 | MAPT (0.47) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL4716959 | 0.75 | DRD2 (0.38) | CHRM1CHRM2CHRM3 | |
| SCHEMBL4593426 | 0.74 | KMT2A (0.34) | MEN1ALDH1A1MAPTKMT2AOPRM1 | |
| SCHEMBL4067285 | 0.74 | CHRM2 (0.36) | CTSKCHRM1GPR119CHRM2CHRM3 | |
| SCHEMBL4658596 | 0.74 | CHRM2 (0.33) | CHRM1IRAK4MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1770086-A1 | Selected CGRP antagonists, process for their preparation as well as their use as medicaments | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | disclosed |