Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327709 | 0.79 | HRH3 (0.59) | HRH3SIGMAR1KCNH2HTR2A | |
| SCHEMBL5159233 | 0.79 | HRH3 (0.55) | HRH3SIGMAR1KCNH2POLBHTR2A | |
| Hydrochloric Acid SCHEMBL5422628 | 0.78 | HRH3 (0.54) | HRH3SIGMAR1KCNH2POLBHTR2A | |
| SCHEMBL7838405 | 0.76 | HRH3 (0.55) | HRH3SIGMAR1KCNH2HTR2A | |
| SCHEMBL22169121 | 0.76 | DRD2 (0.52) | HRH3SIGMAR1KCNH2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL11268933 | 0.75 | HRH3 (0.62) | HRH3SIGMAR1KCNH2POLBMEN1 | |
| SCHEMBL11139082 | 0.75 | ALOX5 (0.49) | ALDH1A1 | |
| SCHEMBL7923985 | 0.75 | HRH3 (0.82) | HRH3SIGMAR1KCNH2MEN1ALDH1A1 | |
| SCHEMBL8565816 | 0.74 | TAAR1 (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7253568 | 0.74 | ALOX5 (0.47) | KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | disclosed |
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044254-A1 | Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers | KRT18, DSP, CDC73 | HRH3 1245/4885SIGMAR1 3538/4885KCNH2 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.