Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163740 | 0.81 | LMNA (0.40) | LMNANPC1RAB9AGAATRPV1 | |
| SCHEMBL5163749 | 0.81 | LMNA (0.40) | LMNANPC1RAB9AGAATRPV1 | |
| SCHEMBL6430156 | 0.77 | LMNA (0.41) | LMNANPC1RAB9AGAAPDE2A | |
| SCHEMBL7085735 | 0.74 | CACNA1B (0.40) | LMNA | |
| SCHEMBL5161679 | 0.71 | LMNA (0.47) | LMNANPC1RAB9AGAA | |
| SCHEMBL27656222 | 0.67 | LMNA (0.56) | LMNANPC1RAB9AGAA | |
| SCHEMBL30102436 | 0.66 | LMNA (0.55) | LMNANPC1RAB9AGAA | |
| SCHEMBL148900 | 0.66 | LMNA (0.55) | LMNANPC1RAB9AGAA | |
| SCHEMBL4195397 | 0.66 | LMNA (0.58) | LMNANPC1RAB9AGAA | |
| SCHEMBL1498542 | 0.66 | KDM4E (0.50) | LMNANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890885-B2 | Herbicidal composition | SYNGENTA CORP PROTECTION, INC. (US) | 2005-05-10 | — | — | US | disclosed |
| EP-1520472-A2 | Herbicidal compositions comprising pyridoyl-1,3-cyclodiones | Syngenta Participations AG (CH) | 2005-04-06 | — | — | EP | disclosed |
| US-20040106519-A1 | Herbicidal composition | SYNGENTA CROP PROTECTION, INC. | 2004-06-03 | — | — | US | disclosed |
| US-6498125-B2 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-12-24 | — | — | US | disclosed |
| EP-1250047-A2 | HERBICIDAL COMPOSITION | Syngenta Participations AG (CH) | 2002-10-23 | — | — | EP | disclosed |
| US-20020016345-A1 | Pyridine ketones useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2002-02-07 | — | — | US | disclosed |
| WO-2001054501-A2 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2001-08-02 | — | — | WO | disclosed |
| EP-1114030-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | Syngenta Participations AG (CH) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015615-A1 | PYRIDINE KETONES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106519-A1 | Herbicidal composition | DDT, ACHE, CYP1B1 | LMNA 4519/4885NPC1 4467/4885RAB9A 4200/4885 |
| US-20020016345-A1 | Pyridine ketones useful as herbicides | DDT, PDHA1, IDH2 | LMNA 4284/4885NPC1 4388/4885RAB9A 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.