Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.67 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.67 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.67 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405727 | 0.89 | ENPP2 (0.73) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL1138626 | 0.82 | ENPP2 (0.53) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL12444126 | 0.82 | — | — | |
| Water SCHEMBL28049243 | 0.82 | KDM4E (0.64) | ENPP2KDM4ETP53MAOAMAOB | |
| SCHEMBL39936 | 0.82 | — | — | |
| SCHEMBL1003006 | 0.82 | TRPV6 (1.00) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL7375936 | 0.79 | KDM4E (0.61) | ENPP2KDM4ETP53MAOAMAOB | |
| SCHEMBL28783861 | 0.79 | KDM4E (0.61) | ENPP2KDM4ETP53MAOAMAOB | |
| Hydrochloric Acid SCHEMBL30942103 | 0.79 | KDM4E (0.61) | ENPP2KDM4ETP53MAOAMAOB | |
| SCHEMBL28251780 | 0.79 | KDM4E (0.61) | ENPP2KDM4ETP53MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771182-A1 | ANTI-PARASITIC USES OF BORINIC ACID COMPLEXES | Anacor Pharmaceuticals, Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | ANACOR PHARMACEUTICALS, INC. | 2006-01-19 | — | — | US | disclosed |
| WO-2005123095-A1 | ANTI-PARASITIC USES OF BORINIC ACID COMPLEXES | ANACOR PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014723-A1 | Anti-parasitic uses of borinic acid complexes | BPGM, HRH1, HRH3 | ORAI1 268/4885ORAI2 367/4885ORAI3 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.