SCHEMBL5164152

SCHEMBL5164152

COC(=O)c1cccc(C(=O)OCC(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
ALDH1A1 P00352 2/20 0.54
LOXL2 Q9Y4K0 1/20 0.53
CYP4F2 P78329 2/20 0.51
CYP4A11 Q02928 2/20 0.51
ADRB2 P07550 7/20 0.51
ADRB1 P08588 7/20 0.51
ADRB3 P13945 7/20 0.51
JMJD6 Q6NYC1 1/20 0.49
SLC7A5 Q01650 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CACNA1F O60840 2/20 0.47
CACNA1D Q01668 2/20 0.47
CACNA1S Q13698 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109308 0.93 ALDH1A1 (0.61) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL10455395 0.87 ALDH1A1 (0.54) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL5164967 0.87 ALDH1A1 (0.54) TSHRALDH1A1CYP4F2CYP4A11ADRB2
SCHEMBL5166149 0.86 TSHR (0.56) TSHRALDH1A1LOXL2ADRB2ADRB1
SCHEMBL19302886 0.84 LOXL2 (0.44) TSHRALDH1A1LOXL2CYP4F2CYP4A11
SCHEMBL5165758 0.84 LMNA (0.60) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL6057072 0.83 ADRB2 (0.66) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL163932 0.83 ADRB2 (0.60) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL163931 0.83 ALDH1A1 (0.54) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL13625751 0.83 LOXL2 (0.47) TSHRALDH1A1LOXL2CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249471-B1 Polypropylene-based resins and polypropylene-based resin compositions PRIME POLYMER CO LTD (JP) 2013-06-26 EP disclosed
EP-0893247-B1 DECORATIVE FILM OR SHEET, AND DECORATIVE MATERIAL AND BUILDING MATERIAL MADE BY USING THE SAME PRIME POLYMER CO LTD (JP) 2007-04-11 EP disclosed
EP-1159315-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
EP-1192196-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-07-13 EP disclosed
EP-1183284-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-04-27 EP disclosed
US-6696380-B2 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2004-02-24 US disclosed
EP-1187857-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2004-01-21 EP disclosed
US-6677410-B2 COORDINATION CATALYSTS EASTMAN CHEMICAL COMPANY 2004-01-13 US disclosed
US-6617008-B1 Decorative film or sheet, and decorative material and building material made by using the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-09-09 US disclosed
US-20030004285-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2003-01-02 US disclosed
US-5241024-A Vapor phase polymerization using catalyst containing chlorinated organic magnesium compound, alcohol, silicone oil, titanium halide, electron donor, organic aluminum compound, cyclic ether NESTE OY KEILANIEMI (FI) 1993-08-31 US disclosed
US-5237013-A A prepolymerized polyolefin in mixture, defect-free film IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1993-08-17 US disclosed
EP-0284005-B1 METHOD OF PRODUCTION OF POLYOLEFINS IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-12-18 EP disclosed
EP-0455813-A1 FLEXIBLE POLYPROPYLENE RESIN, PROPYLENE ELASTOMER COMPOSITION, AND PRODUCTION OF OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-11-13 EP disclosed
EP-0206172-B1 METHOD FOR PRODUCING POLYOLEFINS IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-07-24 EP disclosed
EP-0257131-B1 METHOD FOR PRODUCING BUTENE-1 POLYMER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-05-29 EP disclosed
US-4981930-A POLYMERIZATION CATALYSTS IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-01-01 US disclosed
EP-0284005-A2 Method of production of polyolefins IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-28 EP disclosed
EP-0257131-A2 Method for producing butene-1 polymer IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-03-02 EP disclosed
EP-0206172-A1 Method for producing polyolefins IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1986-12-30 EP disclosed