Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444519 | 0.94 | MAPT (0.50) | ADRB2ADRB1ADRB3MAPTCYP4F2 | |
| SCHEMBL27100548 | 0.89 | MAPT (0.56) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL29702405 | 0.84 | LMNA (0.52) | MAPTALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4449731 | 0.83 | CYP4F2 (0.49) | LOXL2ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL5164152 | 0.83 | TSHR (0.54) | LOXL2ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL14770230 | 0.83 | MAPT (0.59) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL5382671 | 0.82 | MAPT (0.66) | ADRB2ADRB1ADRB3MAPTCYP4F2 | |
| SCHEMBL26185708 | 0.81 | MAPT (0.65) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL27826653 | 0.80 | ALDH1A1 (0.67) | LOXL2CYP4F2CYP4A11ALDH1A1RAB9A | |
| SCHEMBL9770903 | 0.79 | ADRB2 (0.45) | ADRB2ADRB1ADRB3MAPTCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |