Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28183837 | 0.94 | ALDH1A1 (0.53) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL29395733 | 0.88 | RORC (0.70) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL51256 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL124727 | 0.88 | RORC (0.70) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL29350897 | 0.88 | RORC (0.70) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL11180575 | 0.86 | RORC (0.68) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL11466586 | 0.84 | TDP1 (0.55) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL2950255 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL5167842 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL2034981 | 0.82 | RORC (0.80) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417685-B | Non-corresponding selective synthesis of 1-aryl-1H-pyridine [3,4-b ] indole derivatives | 西华大学 | 2019-12-31 | — | — | CN | disclosed |
| US-10196338-B2 | Chiral diamine compounds for the preparation of chiral alcohols and chiral amines | UNIVERSITY COLLEGE DUBLIN (IE) | 2019-02-05 | — | — | US | disclosed |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| CN-107417685-A | Non-corresponding selectivity synthesis 1 aryl 1H pyridines [3,4 b] indole derivatives | 西华大学 | 2017-12-01 | — | — | CN | disclosed |
| US-9795549-B2 | 1,2-alkane polyol-containing composition | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | UNIVERSITY COLLEGE DUBLIN (IE) | 2017-07-20 | — | — | US | disclosed |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | UNIVERSITY COLLEGE DUBLIN (IE) | 2017-07-20 | — | — | US | disclosed |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2016-10-27 | — | — | US | disclosed |
| US-9475743-B2 | Process for the preparation of substituted TRIS(2-hydroxyphenyl)methane | Wintershall Holding GmbH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-4100206-A | Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of keto alcohol compounds | ICI AMERICAS INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100205-A | Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of aminoketo compounds | ICI AMERICAS INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100202-A | Oxidative coupling of alkylphenols or 1-naphthols catalyzed by cupric complexes | ICI AMERICAS INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100203-A | Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of an oxime of a keto or aldehyde compound | ICI AMERICAS INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4098830-A | OXIDATIVE COUPLING OF ALKYLPHENOLS OR 1-NAPHTHOLS CATALYZED BY METAL COMPLEXES OF DICARBOXYLIC ACID COMPOUNDS | ICI AMERICAS INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4097461-A | Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of diketo compounds | ICI AMERICAS INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4096190-A | Oxidative coupling of alkylphenols catalyzed by metal ammonia complexes | ICI AMERICAS INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4085124-A | Oxidative coupling of alkylphenols, alkoxyphenols and 1-naphthols catalyzed by metal complexes of amino compounds | ICI AMERICAS INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4070383-A | COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM | ICI AMERICAS INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4067890-A | Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids | ICI AMERICA INC. (US) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196338-B2 | Chiral diamine compounds for the preparation of chiral alcohols and chiral amines | ADH1C, ADH1A, ADH5 | ALDH1A1 6/4885HPGD 1078/4885ALOX15 2932/4885 |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | ALDH1A1 3275/4885HPGD 2014/4885ALOX15 2583/4885 |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | ADH1C, ADH1A, ADH5 | ALDH1A1 7/4885HPGD 1337/4885ALOX15 3333/4885 |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | ALDH1A1 3275/4885HPGD 2014/4885ALOX15 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.