Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166613 | 0.89 | TYR (0.49) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL3287169 | 0.89 | ALOX5 (0.47) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL18044790 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL5165516 | 0.85 | TRPA1 (0.52) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL5167176 | 0.84 | RNASEH1 (0.55) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL1986274 | 0.83 | ALOX5 (0.46) | ALDH1A1GAAHIF1AALOX5TSHR | |
| SCHEMBL3286189 | 0.82 | ESR1 (0.53) | ALDH1A1GAAHTTALOX5PTGS1 | |
| SCHEMBL50460 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL2202079 | 0.81 | ALOX5 (0.45) | ALDH1A1ALOX12HIF1AALOX5LMNA | |
| SCHEMBL2202101 | 0.80 | ALOX5 (0.44) | HTTALOX5PTGS1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418999-C | Polyestercarbonates and methods of manufacture | GEN ELECTRIC (US) | 2008-09-17 | — | — | CN | claimed |
| CN-1678658-A | Polyestercarbonates and methods of manufacture | GEN ELECTRIC (US) | 2005-10-05 | — | — | CN | claimed |
| CN-1679097-A | Dimensionally stable polycarbonate articles | GEN ELECTRIC (US) | 2005-10-05 | — | — | CN | claimed |
| CN-103781822-B | There is the polymer of the estrogen active of reduction | 索维特殊聚合物有限责任公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-103781822-A | Polymer with reduced estrogenic activity | SOLVAY SPECIALTY POLYMERS USA | 2014-05-07 | — | — | CN | disclosed |
| CN-103361758-A | Coal combustion flue gas filters | SOLVAY ADVANCED POLYMERS LLC | 2013-10-23 | — | — | CN | disclosed |
| CN-101903468-B | Polyphenyl sulfone ketone copolymers | SOLVAY ADVANCED POLYMERS LLC | 2013-10-16 | — | — | CN | disclosed |
| CN-101680126-B | Coal-fired flue gas filter | SOLVAY ADVANCED POLYMERS LLC | 2013-09-18 | — | — | CN | disclosed |
| CN-101817713-B | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-101903468-A | Polyphenyl sulfone ketone copolymers | SOLVAY ADVANCED POLYMERS LLC | 2010-12-01 | — | — | CN | disclosed |
| CN-101817713-A | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2010-09-01 | — | — | CN | disclosed |
| CN-1678658-A | Polyestercarbonates and methods of manufacture | GEN ELECTRIC (US) | 2005-10-05 | — | — | CN | disclosed |
| WO-2005042454-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| WO-2004108642-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004069779-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | WO | disclosed |
| CN-1490318-A | Nitrogen-oxygen heterocyclic compound and preparation method thereof | 长春人造树脂厂股份有限公司 | 2004-04-21 | — | — | CN | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
| CN-1037690-C | (CO)Polycarbonate and process for producing the same | DAICEL CHEM (JP) | 1998-03-11 | — | — | CN | disclosed |
| CN-1092784-A | (being total to) polycarbonate and preparation method thereof | DAICEL CHEM (JP) | 1994-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | ALDH1A1 81/4885GAA 1145/4885HTT 2124/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | ALDH1A1 116/4885GAA 1031/4885HTT 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.