SCHEMBL516630

SCHEMBL516630

O=C(O)Cl.O=C(O)Cl.Oc1ccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
LMNA P02545 3/20 0.52
MAPT P10636 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
OPRK1 P41145 1/20 0.52
POLB P06746 1/20 0.50
GPR55 Q9Y2T6 3/20 0.47
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 2/20 0.47
CHRM2 P08172 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
KCNH2 Q12809 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TYMS P04818 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL4853074 0.93 MEN1 (0.55) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL6756888 0.89 MEN1 (0.59) MEN1KMT2ALMNAMAPTSMN1; SMN2
Phenol SCHEMBL8103114 0.89 MEN1 (0.59) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL29365596 0.89 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL15691572 0.89 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL45826 0.89 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL900116 0.89 MEN1 (0.63) MEN1KMT2ALMNAMAPTSMN1; SMN2
Formaldehyde SCHEMBL972884 0.87 MEN1 (0.57) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL28240230 0.87 MEN1 (0.61) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL18184916 0.84 MMP3 (0.56) MEN1KMT2ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2012-02-02 US disclosed
US-8084553-B2 Curable adhesive compositions, process, and applications TRILLION SCIENCE, INC. (US) 2011-12-27 US disclosed
US-20090181165-A1 Curable adhesive compositions, Process, and applications TRILLION SCIENCE, INC. (US) 2009-07-16 US disclosed
WO-2009089314-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS RBX1, SUZ12, CDH1 MEN1 4614/4885KMT2A 955/4885LMNA 1155/4885
US-20090181165-A1 Curable adhesive compositions, Process, and applications RBX1, SUZ12, CDH1 MEN1 4614/4885KMT2A 955/4885LMNA 1155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.