Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516360 | 0.89 | PPARG (0.47) | — | |
| SCHEMBL7323732 | 0.79 | ALDH1A1 (0.49) | CTSBCYP1A2TDP1 | |
| SCHEMBL7698674 | 0.77 | ATM (0.43) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL7693679 | 0.77 | ATM (0.43) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL28176691 | 0.75 | ATM (0.49) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL10762956 | 0.74 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10770154 | 0.74 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10763164 | 0.74 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL22605148 | 0.72 | ATM (0.41) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL10886030 | 0.71 | SLC7A5 (0.50) | ATMCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074316-A1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOGS | GILON CHAIM (IL) | 2004-09-02 | — | — | WO | claimed |
| EP-0804468-B1 | METHOD OF MAKING AN OMEGA-FUNCTIONALIZED AMINO ACID DERIVATIVE | DEVELOGEN ISRAEL LTD (IL) | 2007-04-25 | — | — | EP | disclosed |
| US-7084244-B2 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2006-08-01 | — | — | US | disclosed |
| WO-2004074316-A1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOGS | GILON CHAIM (IL) | 2004-09-02 | — | — | WO | disclosed |
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2003-07-31 | — | — | US | disclosed |
| US-6407059-B1 | SOMATOSTATIN-TYPE DRUG | PEPTOR LIMITED (IL) | 2002-06-18 | — | — | US | disclosed |
| US-6265375-B1 | Conformationally constrained backbone cyclized peptide analogs | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 2001-07-24 | — | — | US | disclosed |
| EP-0804468-A1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOG | PEPTOR LTD (IL) | 1997-11-05 | — | — | EP | disclosed |
| WO-1995033765-A1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOG | PEPTOR LTD. (IL) | 1995-12-14 | — | — | WO | disclosed |
| EP-0483271-B1 | PEPTIDES CONTAINING DIAMINO-GLYCOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1992003472-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0218688-B1 | DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS | THE UPJOHN COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| WO-1990002137-A1 | RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355065-A1 | Renin inhibitory peptides containing suleptanic acid or derivatives thereof | THE UPJOHN COMPANY (US) | 1990-02-21 | — | — | EP | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | VIP, BDKRB1, BDKRB2 | ATM 3612/4885CTSK 753/4885CTSS 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.