Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823895 | 0.84 | CTSB (0.50) | ALDH1A1CTSBHCAR2TDP1MAPK1 | |
| SCHEMBL7866690 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CTSBHCAR2TDP1MAPK1 | |
| SCHEMBL9179158 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CTSBHCAR2TDP1MAPK1 | |
| SCHEMBL5167644 | 0.79 | ATM (0.46) | CTSBTDP1CYP1A2 | |
| SCHEMBL11115960 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CTSBHCAR2TDP1MAPK1 | |
| SCHEMBL8762963 | 0.78 | CTSB (0.51) | ALDH1A1CTSBHCAR2TDP1MAPK1 | |
| SCHEMBL9516360 | 0.76 | PPARG (0.47) | LTA4HLAP3 | |
| SCHEMBL8393993 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL7419761 | 0.74 | CTSB (0.53) | ALDH1A1CTSBHCAR2TDP1MAPK1 | |
| SCHEMBL27568984 | 0.74 | SLC15A1 (0.53) | ALDH1A1CTSBHCAR2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-B1 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD (CH) | 1994-03-16 | — | — | EP | disclosed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |