Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | YAP1 | P46937 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167644 | 0.89 | ATM (0.46) | — | |
| SCHEMBL4460974 | 0.77 | BCL2 (0.56) | PPARGPPARAYAP1LTA4HBCL2 | |
| SCHEMBL272162 | 0.77 | BCL2 (0.56) | PPARGPPARAYAP1LTA4HBCL2 | |
| SCHEMBL5353421 | 0.77 | BCL2 (0.56) | PPARGPPARAYAP1LTA4HBCL2 | |
| SCHEMBL7323732 | 0.76 | ALDH1A1 (0.49) | LTA4HLAP3 | |
| SCHEMBL3522492 | 0.76 | PPARA (0.56) | PPARGPPARAYAP1MAOBFFAR1 | |
| SCHEMBL3522497 | 0.76 | PPARA (0.56) | PPARGPPARAYAP1MAOBFFAR1 | |
| SCHEMBL7338844 | 0.75 | LTA4H (0.65) | PPARGPPARAMAOBFFAR1FFAR4 | |
| SCHEMBL7339057 | 0.75 | LTA4H (0.65) | PPARGPPARAMAOBFFAR1FFAR4 | |
| SCHEMBL7338836 | 0.75 | LTA4H (0.65) | PPARGPPARAMAOBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293071-B1 | REDOX AMINO ACIDS AND PEPTIDES CONTAINING THEM | UNIVERSITY OF FLORIDA (US) | 1993-09-01 | — | — | EP | disclosed |
| EP-0293071-A1 | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1988-11-30 | — | — | EP | disclosed |