Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL31402461 | 0.71 | LMNA (0.35) | OPRM1KIF11POLBLMNARAB9A | |
| SCHEMBL8766967 | 0.68 | LMNA (0.43) | POLBLMNARECQLRAB9ABLM | |
| SCHEMBL240200 | 0.67 | AKR1C1 (0.48) | OPRM1OPRL1LMNAALDH1A1AKR1C1 | |
| SCHEMBL434296 | 0.66 | KMT2A (0.33) | OPRM1OPRL1RAB9ABLMALDH1A1 | |
| SCHEMBL890180 | 0.65 | AKR1C1 (0.57) | OPRM1OPRL1LMNAALDH1A1AKR1C1 | |
| SCHEMBL31291528 | 0.65 | AKR1C1 (0.42) | LMNATDP1ALDH1A1CES2CES1 | |
| SCHEMBL28956318 | 0.64 | AKR1C1 (0.41) | LMNABLMTDP1ALDH1A1CES2 | |
| SCHEMBL15215650 | 0.62 | AKR1C1 (0.48) | OPRM1OPRL1ALDH1A1AKR1C1MEN1 | |
| SCHEMBL1694005 | 0.62 | ALDH1A1 (0.46) | POLBLMNARECQLRAB9ABLM | |
| SCHEMBL30934615 | 0.62 | OPRM1 (0.42) | OPRM1OPRL1LMNARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773125-A1 | 5-IODOTETRAZOLES | Lanxess Deutschland GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006012996-A1 | 5-IODOTETRAZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |