SCHEMBL434296

SCHEMBL434296

OC1(c2ccccc2)N=NN=N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
P2RX1 P51575 1/20 0.33
P2RX3 P56373 1/20 0.33
P2RX4 Q99571 1/20 0.33
P2RX7 Q99572 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
PKM P14618 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CACNA1F O60840 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
SCN1A P35498 1/20 0.32
SCN4A P35499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280804 0.74 MAOB (0.39) KMT2ACYP2C9HTR2ABLMPMP22
SCHEMBL1067618 0.74 OPRL1 (0.33) KMT2AP2RX1P2RX3P2RX4P2RX7
SCHEMBL5274311 0.72 OPRM1 (0.33) KMT2AOPRM1OPRK1OPRL1MAPT
SCHEMBL1284435 0.72 KMT2A (0.32) KMT2AP2RX1P2RX3P2RX4P2RX7
Bromide SCHEMBL29801969 0.70 OPRM1 (0.32) KMT2AOPRM1OPRK1OPRL1MAPT
Bromide SCHEMBL28070425 0.70 OPRM1 (0.32) KMT2AOPRM1OPRK1OPRL1MAPT
SCHEMBL3925565 0.70 GAA (0.41) KMT2AP2RX1P2RX3P2RX4P2RX7
SCHEMBL27746475 0.69 AKR1C1 (0.42) KMT2AMEN1PKMALDH1A1AKR1C1
SCHEMBL474067 0.68 OPRM1 (0.31) OPRM1OPRK1OPRL1MAPT
SCHEMBL5274478 0.68 ALDH1A1 (0.31) KMT2ARAB9AOPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468438-B2 Process for the semisynthesis of deserpidine INDENA S.P.A. (IT) 2008-12-23 US claimed
US-20080242864-A1 Process for the Semisynthesis of Deserpidine INDENA S.P.A. (IT) 2008-10-02 US claimed
EP-1737855-B1 A PROCESS FOR THE SEMISYNTHESIS OF DESERPIDINE INDENA SPA (IT) 2008-06-25 EP claimed
JP-2007530467-A 2007-11-01 JP claimed
EP-1737855-A1 A PROCESS FOR THE SEMISYNTHESIS OF DESERPIDINE Indena S.P.A. (IT) 2007-01-03 EP claimed
WO-2005095394-A1 A PROCESS FOR THE SEMISYNTHESIS OF DESERPIDINE INDENA S.P.A. (IT) 2005-10-13 WO claimed
EP-0170164-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
US-H122-H PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US claimed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP claimed
EP-3270430-B1 ORGANIC SEMICONDUCTOR FILM FORMATION COMPOSITION, ORGANIC THIN FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORP (JP) 2020-12-09 EP disclosed
EP-2718753-A1 COLOR FILTER, CCD SENSOR, CMOS SENSOR, ORGANIC CMOS SENSOR, AND SOLID-STATE IMAGE SENSOR FUJIFILM Corporation (JP) 2014-04-16 EP disclosed
WO-2014034533-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE AND ELECTRONIC DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-03-06 WO disclosed
WO-2014017408-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD USING THE COMPOSITION, AND ELECTRONIC DEVICE PRODUCING METHOD AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2014-01-30 WO disclosed
EP-2596066-A1 DYE COMPOUND, METHOD OF PRODUCING DIPYRROMETHENE METAL COMPLEX COMPOUND, METHOD OF PRODUCING DYE MULTIMER, SUBSTITUTED PYRROLE COMPOUND, COLORED CURABLE COMPOSITION, COLOR FILTER, METHOD OF PRODUCING COLOR FILTER, SOLID-STATE IMAGE SENSOR AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM Corporation (JP) 2013-05-29 EP disclosed
US-4540654-A Method of forming color image comprising heterocyclic magenta dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1985-09-10 US disclosed
US-4500630-A USING AN IMIDAZOLO(1,2-B)PYRAZOLE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed
EP-0127162-A2 Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-12-05 EP disclosed
EP-0119741-A2 Method of producing magenta images in silver halide colour photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed
EP-0119860-A2 Pyrazolo magenta couplers used in silver halide photography FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed
US-4009038-A CYAN COUPLER, A 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242864-A1 Process for the Semisynthesis of Deserpidine CYP51A1, CYP4A11, QDPR KMT2A 729/4885P2RX1 3457/4885P2RX3 3473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.