Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SQLE | Q14534 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9052381 | 0.98 | LMNA (0.35) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| Hydrochloric Acid SCHEMBL6059948 | 0.98 | LMNA (0.35) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| SCHEMBL8702270 | 0.78 | KDM1A (0.35) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| SCHEMBL8699572 | 0.78 | KDM1A (0.35) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| Hydrochloric Acid SCHEMBL9052404 | 0.77 | KDM1A (0.38) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| Hydrochloric Acid SCHEMBL9052408 | 0.77 | KDM1A (0.38) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| SCHEMBL8702258 | 0.75 | KDM1A (0.33) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| SCHEMBL8702250 | 0.75 | KDM1A (0.33) | LMNAADRA2ACYP2D6SLC6A2SQLE | |
| Hydrochloric Acid SCHEMBL9051545 | 0.74 | KDM1A (0.35) | — | |
| Hydrochloric Acid SCHEMBL9051551 | 0.74 | KDM1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1561744-B1 | AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT | POLA CHEM IND INC (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1020426-B9 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEM IND INC (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-20060004230-A1 | Process for the preparation of terbinafine and salts thereof | CHEMAGIS LTD. (IL) | 2006-01-05 | — | — | US | disclosed |
| EP-1561744-A2 | AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT | POLA CHEMICAL INDUSTRIES INC. (JP) | 2005-08-10 | — | — | EP | disclosed |
| EP-1020426-B1 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEM IND INC (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1112998-B1 | AMINE DERIVATIVES | POLA CHEM IND INC (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-6586633-B1 | Antifungal agents | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2003-07-01 | — | — | US | disclosed |
| US-6570044-B2 | Using Grignard reagent or metallic lithium in place of the highly pyrophoric butyllithium as proton extracting agent; intermediate in production of terbinafine | CHEMAGIS LTD. (IL) | 2003-05-27 | — | — | US | disclosed |
| US-20020016517-A1 | Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol | CHEMAGIS LTD. (IL) | 2002-02-07 | — | — | US | disclosed |
| EP-1174407-A2 | A process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol | CHEMAGIS LTD. (IL) | 2002-01-23 | — | — | EP | disclosed |
| US-6329399-B1 | Antifungal amine derivatives and processing for producing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1112998-A1 | AMINE DERIVATIVES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-1020426-A1 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-19 | — | — | EP | disclosed |
| JP-2000063348-A | AROMATIC ANTIFUNGAL AGENT | POLA CHEM IND INC | 2000-02-29 | — | — | JP | disclosed |
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0395768-A1 | SUBSTITUTED ALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4737516-A | FUNGICIDES | SANDOZ LTD. (CH) | 1988-04-12 | — | — | US | disclosed |
| US-4382951-A | FUNGICIDES | SANDOZ LTD. (CH) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016517-A1 | Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol | FUT6, ACR, HCN2 | LMNA 200/4885ADRA2A 4193/4885CYP2D6 308/4885 |
| US-20060004230-A1 | Process for the preparation of terbinafine and salts thereof | TPMT, HNMT, DHPS | LMNA 3328/4885ADRA2A 3672/4885CYP2D6 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.