Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243145 | 0.76 | LIMK1 (0.34) | LIMK1 | |
| SCHEMBL5244491 | 0.73 | LIMK1 (0.61) | LIMK1 | |
| SCHEMBL5245414 | 0.69 | PIM1 (0.48) | — | |
| SCHEMBL16751693 | 0.67 | GABRA1 (0.48) | — | |
| SCHEMBL16751768 | 0.66 | GABRA1 (0.42) | LIMK1 | |
| SCHEMBL17117837 | 0.65 | ALDH1A1 (0.41) | LIMK1 | |
| SCHEMBL25461826 | 0.64 | LMNA (0.40) | LIMK1 | |
| SCHEMBL17917464 | 0.64 | EGFR (0.31) | LIMK1 | |
| SCHEMBL16751602 | 0.63 | GABRA1 (0.46) | — | |
| SCHEMBL2301375 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773840-A1 | SUBSTITUTED PYRIDO[3',2':4,5]THIENO[3,2-D]PYRIMIDINES AND PYRIDO[3',2':4,5]FURO[3,2-D]-PYRIMIDINES FOR USE AS INHIBITORS OF PDA-4 AND/OR TNF-ALPHA RELEASE | Curacyte Discovery GmbH (DE) | 2007-04-18 | — | — | EP | claimed |
| WO-2006010567-A1 | SUBSTITUTED PYRIDO[3', 2': 4, 5]THIENO[3,2-D]PYRIMIDINES AND PYRIDO[3', 2': 4, 5]FURO[3, 2, D]PYRIMIDINES USED AS INHIBITORS OF THE PDE-4 AND/OR THE RELEASE OF TNF$G(A) | CURACYTE DISCOVERY GMBH (DE) | 2006-02-02 | — | — | WO | claimed |