Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243274 | 0.76 | LIMK1 (0.52) | LIMK1 | |
| SCHEMBL5170687 | 0.76 | LIMK1 (0.37) | LIMK1 | |
| SCHEMBL16751693 | 0.74 | GABRA1 (0.48) | — | |
| SCHEMBL16751768 | 0.70 | GABRA1 (0.42) | LIMK1 | |
| SCHEMBL16751602 | 0.68 | GABRA1 (0.46) | — | |
| SCHEMBL25461826 | 0.66 | LMNA (0.40) | LIMK1 | |
| SCHEMBL16751705 | 0.65 | LIMK1 (0.39) | LIMK1 | |
| SCHEMBL17117837 | 0.64 | ALDH1A1 (0.41) | LIMK1 | |
| SCHEMBL16751643 | 0.63 | HTR2C (0.39) | LIMK1 | |
| SCHEMBL17917464 | 0.63 | EGFR (0.31) | LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819710-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058724-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-08 | — | — | WO | disclosed |