Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.33 |
| ▸ | SNRNP200 | O75643 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171897 | 0.87 | NOTUM (0.35) | USP30SNRNP200SCDRBP4 | |
| SCHEMBL5172261 | 0.84 | KLKB1 (0.38) | USP30KLKB1RIPK1SCDRBP4 | |
| SCHEMBL5171053 | 0.83 | HRH3 (0.35) | SCDBRD4 | |
| SCHEMBL5171322 | 0.81 | FNTA (0.34) | — | |
| SCHEMBL5171939 | 0.80 | HRH3 (0.40) | — | |
| SCHEMBL5172025 | 0.80 | HRH3 (0.39) | — | |
| SCHEMBL5169168 | 0.79 | PRMT5 (0.37) | — | |
| SCHEMBL5170176 | 0.77 | SLC18A2 (0.36) | — | |
| SCHEMBL5194064 | 0.77 | HRH3 (0.40) | — | |
| SCHEMBL5170187 | 0.77 | SLC18A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778643-A1 | TETRAHYDROBENZAZEPINES AS ANTAGONISTS AND/OR REVERSE AGONISTS OF THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006018260-A1 | TETRAHYDROBENZAZEPINES AS ANTAGONISTS AND/OR REVERSE AGONISTS OF THE HISTAMINE H 3 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |