Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770625 | 0.80 | NPBWR1 (0.43) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2061964 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL25027280 | 0.77 | GAA (0.45) | ALDH1A1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL31053862 | 0.77 | GAA (0.45) | ALDH1A1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL2483950 | 0.75 | HTR6 (0.62) | ALDH1A1MAPK1MAPTHTT | |
| SCHEMBL12205180 | 0.75 | HTR6 (0.36) | ALDH1A1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL30657603 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAPTPOLBNPC1 | |
| SCHEMBL29126953 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAPTPOLBNPC1 | |
| SCHEMBL30745155 | 0.72 | MGLL (0.50) | ALDH1A1MAPK1KMT2AMAPTMEN1 | |
| SCHEMBL29151112 | 0.72 | MGLL (0.50) | ALDH1A1MAPK1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737826-A1 | ALPHA-4 INTEGRIN MEDIATED CELL ADHESION INHIBITORS FOR THE TREATMENT OR PREVENTION OF INFLAMMATORY DISEASES | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005075438-A1 | ALPHA-4 INTEGRIN MEDIATED CELL ADHESION INHIBITORS FOR THE TREATMENT OR PREVENTION OF INFLAMMATORY DISEASES | TANABE SEIYAKU CO., LTD. (JP) | 2005-08-18 | — | — | WO | disclosed |