SCHEMBL51743

SCHEMBL51743

CCN(CC)C(=Cc1ccccc1)c1c2ccccc2cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 1/20 0.42
GLA P06280 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ACACB O00763 2/20 0.38
ACACA Q13085 2/20 0.38
NR1I2 O75469 1/20 0.37
KDM1A O60341 1/20 0.35
TSHR P16473 2/20 0.35
NPSR1 Q6W5P4 2/20 0.34
ABCC1 P33527 1/20 0.34
MAPT P10636 1/20 0.34
APAF1 O14727 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533166 0.81 KDM4E (0.42) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL12411252 0.77 NPC1 (0.49) MEN1KMT2AALDH1A1HPGDCYP2C19
SCHEMBL11206642 0.77 NPC1 (0.49) MEN1KMT2AALDH1A1HPGDCYP2C19
SCHEMBL5408079 0.74 L3MBTL1 (0.41) MEN1KMT2AALDH1A1NPC1L3MBTL1
SCHEMBL31414402 0.72 ALDH1A1 (0.53) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL28123917 0.72 ALDH1A1 (0.53) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL2494588 0.71 MEN1 (0.51) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL5709306 0.70 ALDH1A1 (0.47) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL9804059 0.70 CYP19A1 (0.47) MEN1KMT2AKDM4EALDH1A1CYP1A2
SCHEMBL18938581 0.70 ALDH1A1 (0.39) MEN1KMT2AALDH1A1L3MBTL1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6521386-B1 High photoresponse, durability, high speed RICOH COMPANY LTD. (JP) 2003-02-18 US claimed
JP-56144432-A None JP disclosed
EP-1734410-B1 ELECTROPHOTOGRAPHY PHOTOSENSITIVE BODY, METHOD FOR PRODUCING ELECTROPHOTOGRAPHY PHOTOSENSITIVE BODY, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPH CANON KK (JP) 2016-05-11 EP disclosed
EP-2527922-B1 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, method of producing electrophotographic photosensitive member, and urea compound CANON KK (JP) 2015-08-05 EP disclosed
US-8962227-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, method of producing electrophotographic photosensitive member, and urea compound CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
EP-1734411-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC DEVICE CANON KK (JP) 2013-05-15 EP disclosed
US-8431305-B2 Capsule toner, two-component developer, and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2013-04-30 US disclosed
US-8399171-B2 Method of manufacturing resin-layer coated carrier, resin-layer coated carrier, developer, developing device, and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2013-03-19 US disclosed
US-8399168-B2 Method for producing toner, two-component developer, developing device and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2013-03-19 US disclosed
US-8389194-B2 Method of manufacturing toner, toner obtained by method thereof, one-component developer, two-component developer, developing device and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2013-03-05 US disclosed
US-4946766-A Electrophotographic photoconductor having intermediate layer comprising indium oxide RICOH COMPANY, LTD. (JP) 1990-08-07 US disclosed
US-4906545-A Electrophotographic photoconductor with undercoat layer containing metal oxide on support RICOH COMPANY, LTD. (JP) 1990-03-06 US disclosed
US-4871635-A REUSABLE, NONDEGRADATING IN HUMIDITY RICOH COMPANY, LTD. (JP) 1989-10-03 US disclosed
US-4863822-A Electrophotographic photoconductor comprising charge generating and transport layers containing adjuvants RICOH COMPANY LTD. (JP) 1989-09-05 US disclosed
US-4837120-A RESIN RELEASES LITTLE OR NO AMMONIA RICOH COMPANY, LTD. (JP) 1989-06-06 US disclosed
EP-0012611-B1 ELECTROPHOTOGRAPHIC ELEMENT Ricoh Company, Ltd (JP) 1983-10-05 EP disclosed
US-4348470-A IN CHARGE GENERATING LAYER RICOH CO., LTD. (JP) 1982-09-07 US disclosed
US-4301224-A CHARGE TRANSPORT LAYER FORMED BY ADDING AN ORGANIC PIGMENT TO A SOLVENT AND TWO DIFFERENT RESINS RICOH CO., LTD. (JP) 1981-11-17 US disclosed
JP-S56144432-A LAMINATE TYPE ELECTROPHOTOGRAPHIC RECEPTOR RICOH CO LTD 1981-11-10 JP disclosed
EP-0012611-A2 Electrophotographic element Ricoh Company, Ltd (JP) 1980-06-25 EP disclosed