Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287865 | 0.98 | KCNH2 (0.42) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL4473252 | 0.94 | — | — | |
| SCHEMBL25543688 | 0.74 | LMNA (0.37) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20210119 | 0.73 | CTSK (0.37) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL27949105 | 0.73 | CTSK (0.37) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL21186379 | 0.72 | PRSS1 (0.38) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL16068283 | 0.71 | — | — | |
| SCHEMBL358647 | 0.71 | — | — | |
| SCHEMBL3394938 | 0.70 | EPHX2 (0.54) | KCNH2MAPTESR1ADRA2AADORA3 | |
| SCHEMBL3924849 | 0.69 | EPHX2 (0.57) | KCNH2MAPTESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | claimed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | claimed |
| JP-5186440-A | — | — | None | — | — | JP | disclosed |
| CN-106432216-B | The preparation method and application of the pyrazol acid amide compounds of the isoxazole structure of aryl containing 5- | 南通大学 | 2019-09-20 | — | — | CN | disclosed |
| EP-2944636-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-09-04 | — | — | EP | disclosed |
| CN-106432216-A | Preparation method and application of pyrazol amide compound containing 5-aryl isoxazole structure | 南通大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-106432216-A | Preparation method and application of pyrazol amide compound containing 5-aryl isoxazole structure | 南通大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-106432216-A | Preparation method and application of pyrazol amide compound containing 5-aryl isoxazole structure | 南通大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-1758896-A1 | PYRIDINYL-ISOXAZOLES AND THEIR USE AS HERBICIDES | Bayer CropScience GmbH (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123726-A1 | PYRIDINYL-ISOXAZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-12-29 | — | — | WO | disclosed |
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
| US-5827869-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |
| WO-1997029748-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-21 | — | — | WO | disclosed |
| US-5612359-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0702012-A1 | Substituted isoxazole sulfonamides and their use as endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| JP-H05186440-A | NEW HERBICIDE | RHONE POULENC AGRICULTURE LTD | 1993-07-27 | — | — | JP | disclosed |
| CN-1068567-A | NEW HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1993-02-03 | — | — | CN | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | PRDX1, CYP4X1, PRDX4 | CYP1A2 21/4885CYP19A1 241/4885CYP2C9 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.