SCHEMBL517540

SCHEMBL517540

O=C(CCCCC(=O)Nc1ccc(C2CCCCC2)cc1)Nc1ccc(C2CCCCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.63
KLF5 Q13887 1/20 0.63
ALDH1A1 P00352 6/20 0.62
HPGD P15428 2/20 0.62
USP2 O75604 2/20 0.59
NPC1 O15118 2/20 0.59
HDAC3 O15379 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
DEGS1 O15121 1/20 0.56
RORC P51449 1/20 0.55
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7940080 0.94 MITF (0.58) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL6389391 0.93 HDAC6 (0.58) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL7365654 0.88 HDAC3 (0.61) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL7735911 0.84 MITF (0.63) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL3824110 0.84 MITF (0.63) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL10115164 0.83 RORC (0.50) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL10115488 0.83 RORC (0.50) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL11356835 0.81 HDAC8 (0.64) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL11215485 0.80 HDAC8 (0.62) MITFKLF5ALDH1A1HPGDUSP2
SCHEMBL7738147 0.79 ALDH1A1 (0.81) MITFKLF5ALDH1A1HPGDUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021069690-A1 FILM THAI POLYETHYLENE CO., LTD. (TH) 2021-04-15 WO claimed
US-10011709-B2 Compositions comprising propylene-based elastomers and polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-03 US claimed
US-20170362421-A1 Compositions Comprising Propylene-Based Elastomers and Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-12-21 US claimed
WO-2016137559-A1 COMPOSITIONS COMPRISING PROPYLENE-BASED ELASTOMERS AND POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-01 WO claimed
US-6235823-B1 CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-05-22 US claimed
EP-0557721-B1 Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. NEW JAPAN CHEM CO LTD (JP) 2000-10-04 EP claimed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP claimed
WO-2021069690-A1 FILM THAI POLYETHYLENE CO., LTD. (TH) 2021-04-15 WO disclosed
US-10011709-B2 Compositions comprising propylene-based elastomers and polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-03 US disclosed
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-20170362421-A1 Compositions Comprising Propylene-Based Elastomers and Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-12-21 US disclosed
WO-2016137559-A1 COMPOSITIONS COMPRISING PROPYLENE-BASED ELASTOMERS AND POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-01 WO disclosed
US-9023921-B2 Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin NEW JAPAN CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0962489-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-12-08 EP disclosed
US-5716998-A PARTICLES COMPRISING POLYPROPYLENE RESIN AND DIAMIDE COMPOUND AS BETA-FORM NUCLEATING AGENT KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-02-10 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
EP-0790275-A1 PREFOAMED PARTICLES OF POLYPROPYLENE RESIN AND PROCESS FOR PRODUCING THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-08-20 EP disclosed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP disclosed