Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772682 | 0.77 | ALDH1A1 (0.38) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1940345 | 0.73 | ACHE (0.45) | L3MBTL1HSD17B10TSHRHBBKDM4E | |
| SCHEMBL8947000 | 0.71 | ACHE (0.43) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11789849 | 0.71 | ACHE (0.45) | L3MBTL1HSD17B10TSHRHBBKDM4E | |
| SCHEMBL5176224 | 0.70 | TSHR (0.39) | L3MBTL1HSD17B10TSHRHBBKDM4E | |
| SCHEMBL9120848 | 0.70 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL9246318 | 0.70 | NPC1 (0.45) | HSD17B10KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL11542763 | 0.68 | KDM4E (0.47) | L3MBTL1HSD17B10KDM4ENQO1ALDH1A1 | |
| SCHEMBL9244949 | 0.67 | KDM4E (0.50) | HSD17B10TSHRKDM4ENQO1ALDH1A1 | |
| SCHEMBL6559812 | 0.66 | KDM4E (0.49) | L3MBTL1HSD17B10TSHRHBBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812404-A1 | INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS | LABORATOIRE THERAMEX (MC) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006040351-A1 | INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS | LABORATOIRE THERAMEX (MC) | 2006-04-20 | — | — | WO | disclosed |