Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772721 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTNPC1HPGD | |
| SCHEMBL8772812 | 0.77 | ENPP2 (0.38) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5178348 | 0.77 | L3MBTL1 (0.44) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8947000 | 0.71 | ACHE (0.43) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL25459991 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTNPC1HPGD | |
| SCHEMBL20054857 | 0.70 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL4170324 | 0.66 | CYP11B1 (0.52) | ALDH1A1KDM4EMAPTNPC1HPGD | |
| SCHEMBL3720728 | 0.64 | PTGS1 (0.59) | ALDH1A1KDM4EMAPTNPC1HPGD | |
| SCHEMBL7034663 | 0.64 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL12687891 | 0.64 | CYP2D6 (0.68) | ALDH1A1KDM4EMAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789692-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1997-08-20 | — | — | EP | disclosed |