Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596926 | 0.86 | MEN1 (0.48) | ACHEALDH1A1CYP3A4NCF1MEN1 | |
| SCHEMBL21596938 | 0.75 | LMNA (0.37) | ALDH1A1LMNATP53CA2 | |
| SCHEMBL21596940 | 0.72 | ENPP2 (0.45) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9214142 | 0.72 | NR4A2 (0.47) | ACHEALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL6952286 | 0.71 | CLK1 (0.50) | ALDH1A1CYP3A4KDM4ENPC1LMNA | |
| SCHEMBL5178348 | 0.71 | L3MBTL1 (0.44) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8772682 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11195844 | 0.70 | ALDH1A1 (0.52) | ACHEALDH1A1CYP3A4NCF1MEN1 | |
| SCHEMBL21596922 | 0.68 | KMT2A (0.50) | ALDH1A1CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL3841526 | 0.68 | HTR1A (0.58) | ALDH1A1CYP3A4NCF1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580982-A | ANTIDEPRESSANTS; ANTICHOLINERGIC AGENTS; ALZHEIMER'S DISEASE; AMINE OXIDASE INHIBITORS | HOECHST MARION ROUSSEL INC. (US) | 1996-12-03 | — | — | US | disclosed |