Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201041 | 0.77 | ESR1 (0.37) | LMNAPPARDPPARAPPARGTP53 | |
| SCHEMBL2095367 | 0.75 | LMNA (0.49) | LMNAPPARDPPARAPPARGTSHR | |
| SCHEMBL14564345 | 0.75 | LMNA (0.50) | LMNATSHRTP53SMN1; SMN2RXFP1 | |
| SCHEMBL2091728 | 0.74 | LMNA (0.48) | LMNAPPARDPPARAPPARGTSHR | |
| SCHEMBL5176741 | 0.74 | CTSG (0.42) | LMNAPPARDPPARAPPARGTSHR | |
| SCHEMBL14564347 | 0.73 | TP53 (0.49) | LMNAPPARDPPARAPPARGTSHR | |
| SCHEMBL14564404 | 0.73 | KEAP1 (0.55) | LMNAPPARDPPARAPPARGTP53 | |
| SCHEMBL5178978 | 0.72 | LMNA (0.58) | LMNATP53SMN1; SMN2RXFP1CA2 | |
| SCHEMBL8690419 | 0.71 | ITGB3 (0.48) | LMNATP53SMN1; SMN2RXFP1CA2 | |
| SCHEMBL8694295 | 0.70 | LMNA (0.47) | LMNATP53SMN1; SMN2RXFP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362854-B1 | Benzo[b[thiophene derivatives and process for producing the same | TEIJIN PHARMA LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1792614-A1 | Benzo[b]thiophene derivatives | Teijin Pharma Limited (JP) | 2007-06-06 | — | — | EP | disclosed |
| US-6884896-B2 | Benzo[b]thiophene derivatives and process for preparing the same | TEIJIN LIMITED (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1362854-A1 | BENZO b]THIOPHENE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-20030176490-A1 | Benzo(b)thiophene derivatives and process for producing the same | TEIJIN PHARMA LIMITED (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176490-A1 | Benzo(b)thiophene derivatives and process for producing the same | CYP4B1, CYP1B1, CYP3A4 | LMNA 4525/4885PPARD 3519/4885PPARA 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.