Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178565 | 0.77 | LMNA (0.43) | LMNAMAPTPPARDPPARAPPARG | |
| SCHEMBL15211479 | 0.69 | HSD11B1 (0.43) | ESR1MAPTPPARDPPARAPPARG | |
| SCHEMBL9751544 | 0.69 | ALOX15 (0.43) | LMNAMAPTTP53ALDH1A1HSD17B10 | |
| SCHEMBL18791161 | 0.68 | LMNA (0.38) | BCL2L1MCL1LMNAMAPTTP53 | |
| SCHEMBL15211572 | 0.68 | PPARD (0.39) | ESR1LMNAMAPTPPARDPPARA | |
| SCHEMBL6130768 | 0.67 | TBXAS1 (0.50) | BCL2L1MCL1LMNAMAPTALDH1A1 | |
| SCHEMBL15211511 | 0.67 | CYP3A4 (0.41) | ESR1MAPTALDH1A1HSD17B10GAA | |
| SCHEMBL10952907 | 0.67 | NR4A2 (0.51) | BCL2L1MCL1MAPTALDH1A1HSD17B10 | |
| SCHEMBL9872338 | 0.66 | LMNA (0.57) | LMNAALDH1A1CYP2C9GAA | |
| SCHEMBL5179107 | 0.66 | MAPT (0.54) | BCL2L1MCL1LMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362854-B1 | Benzo[b[thiophene derivatives and process for producing the same | TEIJIN PHARMA LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1792614-A1 | Benzo[b]thiophene derivatives | Teijin Pharma Limited (JP) | 2007-06-06 | — | — | EP | disclosed |
| US-6884896-B2 | Benzo[b]thiophene derivatives and process for preparing the same | TEIJIN LIMITED (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1362854-A1 | BENZO b]THIOPHENE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-20030176490-A1 | Benzo(b)thiophene derivatives and process for producing the same | TEIJIN PHARMA LIMITED (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176490-A1 | Benzo(b)thiophene derivatives and process for producing the same | CYP4B1, CYP1B1, CYP3A4 | ESR1 1360/4885BCL2L1 2379/4885MCL1 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.