SCHEMBL518017

SCHEMBL518017

CP(=O)(O)OP(C)(=O)O.OCC(CO)(CO)CO

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.35
PPARD Q03181 1/20 0.34
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
FDPS P14324 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Phosphonate SCHEMBL134903 0.83 CA2 (0.53) CA2ALDH1A1MAPK1FDPSBLM
SCHEMBL29185221 0.83 CA2 (0.44) CA2ALDH1A1MAPK1FDPSBLM
SCHEMBL3364605 0.80
Pyrophosphoric Acid SCHEMBL134478 0.78 FDPS (0.59) PPARDALDH1A1TP53CYP3A4MAPK1
Pyrophosphoric Acid SCHEMBL9719630 0.78 FDPS (0.59) PPARDALDH1A1TP53CYP3A4MAPK1
Pyrophosphoric Acid SCHEMBL9416490 0.78 FDPS (0.59) PPARDALDH1A1TP53CYP3A4MAPK1
Phosphoric Acid SCHEMBL23777274 0.76 ALDH1A1 (0.39) CA2ALDH1A1MAPK1FDPS
Phosphoric Acid SCHEMBL7139936 0.76 ALDH1A1 (0.39) CA2ALDH1A1MAPK1FDPS
Phosphoric Acid SCHEMBL133397 0.76 ALDH1A1 (0.39) CA2ALDH1A1MAPK1FDPS
Phosphoric Acid SCHEMBL135754 0.76 ALDH1A1 (0.39) CA2ALDH1A1MAPK1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020058116-A1 FLAME RETARDANT POLYPROPYLENE COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-26 WO disclosed
US-20140323606-A1 RUBBER-MODIFIED FLAME-RETARDANT MOULDING COMPOSITIONS AND PRODUCTION THEREOF BASF SE (DE) 2014-10-30 US disclosed
US-8450407-B2 Heat aging-resistant polyamides with flame retardancy BASF SE (DE) 2013-05-28 US disclosed
US-8293823-B2 moldings comprising phosphorus-containing, nitrogen-containing compounds, condensates or mixtures as flameproofing agents, polycarbonates, polyesters and adjuvants BASF SE (DE) 2012-10-23 US disclosed
US-20120208937-A1 HEAT AGING-RESISTANT POLYAMIDES WITH FLAME RETARDANCY BASF SE (DE) 2012-08-16 US disclosed
US-20120029122-A1 FLAME RETARDANT MOLDING COMPOSITIONS BASF SE (DE) 2012-02-02 US disclosed
US-20110274932-A1 COMPONENT COMPRISING AN INSERT PART AND PLASTICS JACKETING, AND PROCESS FOR PRODUCTION OF THE COMPONENT BASF SE (DE) 2011-11-10 US disclosed
US-20110118371-A1 RUBBER-MODIFIED FLAME-RETARDANT MOLDING COMPOUNDS BASF SE (DE) 2011-05-19 US disclosed
US-20110028613-A1 FLAME-RETARDENT THERMOPLASTIC COMPOSITIONS BASF SE (DE) 2011-02-03 US disclosed
US-20080194741-A1 Flowable Thermoplastic Materials With Halogen-Free Flame Protection BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20070197696-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-08-23 US disclosed
US-20070167544-A1 Ignition resistant polycarbonate polyester composition GENERAL ELECTRIC COMPANY 2007-07-19 US disclosed
US-6716899-B1 FLOWABILITY; MOLD DEPOSITS GREATLY REDUCED; ELECTRICAL PARTS; A METAL PHOSPHINATE OR A DIPHOSPHINATE; ORGANOPHOSPHORUS FLAME RETARDANT BASF AKTIENGESELLSCHAFT (DE) 2004-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028613-A1 FLAME-RETARDENT THERMOPLASTIC COMPOSITIONS FRG1, FEM1B, FLNB CA2 4270/4885PPARD 1943/4885ALDH1A1 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.