Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 3/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | ELOC | Q15369 | 1/20 | 0.33 |
| ▸ | ELOB | Q15370 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180710 | 1.00 | AOC2 (0.35) | AOC2VHLELOCELOBPOLB | |
| SCHEMBL4179681 | 0.77 | KDM4E (0.39) | POLBMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL4179685 | 0.77 | KDM4E (0.39) | POLBMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL12123975 | 0.75 | LMNA (0.35) | AOC2VHLELOCELOBPOLB | |
| SCHEMBL5180033 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNA | |
| SCHEMBL5180028 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4186688 | 0.71 | VHL (0.39) | AOC2VHLELOCELOBPOLB | |
| SCHEMBL5180770 | 0.67 | KDM4E (0.34) | KDM4E | |
| SCHEMBL5180767 | 0.67 | KDM4E (0.34) | KDM4E | |
| SCHEMBL4179666 | 0.66 | L3MBTL1 (0.49) | POLBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | claimed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | claimed |
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | disclosed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | MC1R, MC5R, MC3R | AOC2 1158/4885VHL 1931/4885ELOC 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.