Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736831 | 1.00 | KYNU (0.60) | KYNUALDH1A1ALOX15PSMB1CTSK | |
| SCHEMBL7688519 | 0.92 | PSMB1 (0.57) | PSMB1CTSKPSMB8PSMB5CTSS | |
| SCHEMBL8078067 | 0.90 | PSMB1 (0.56) | PSMB1CTSKPSMB8PSMB5CTSS | |
| SCHEMBL7742003 | 0.89 | PSMB1 (0.56) | ALDH1A1ALOX15PSMB1CTSKPSMB8 | |
| SCHEMBL7742845 | 0.89 | PSMB1 (0.56) | ALDH1A1ALOX15PSMB1CTSKPSMB8 | |
| SCHEMBL10746345 | 0.89 | CAPN1 (0.61) | ALDH1A1ALOX15PSMB1CTSKPSMB8 | |
| SCHEMBL10746340 | 0.89 | CAPN1 (0.61) | ALDH1A1ALOX15PSMB1CTSKPSMB8 | |
| SCHEMBL13724740 | 0.89 | CASP1 (0.64) | KYNUALDH1A1ALOX15CTSKCASP1 | |
| SCHEMBL1067460 | 0.89 | CASP1 (0.64) | KYNUALDH1A1ALOX15CTSKCASP1 | |
| SCHEMBL19695419 | 0.89 | CASP1 (0.64) | KYNUALDH1A1ALOX15CTSKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236716-B1 | Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2007-04-11 | — | — | EP | disclosed |
| EP-1236716-A1 | Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative | TORAY INDUSTRIES, INC. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6420166-B2 | REACTING AN N-PROTECTED ASPARAGINE ESTER WITH A PROTEASE IN AQUEOUS SOLUTION AT PH OF 6.0 TO 7.5 AND AN ORGANIC SOLVENT, AND EXTRACTING THE N-PROTECTED-D-ASPARAGINE ESTER; CHEMICAL INTERMEDIATES TO ANTIBACTERIAL COMPOUNDS | BASOLEA PHARMACEUTICA AG (CH) | 2002-07-16 | — | — | US | disclosed |
| US-6348600-B1 | CYCLIZING OPTICALLY ACTIVE ASPARAGINE ESTER DERIVATIVE OR ACID SALT THEREOF BY DISSOLVING COMPOUND IN SOLVENT | TORAY INDUSTRIES, INC. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-20010049127-A1 | Process for the preparation of D-asparagine derivatives | HOFFMANN-LA ROCHE INC. | 2001-12-06 | — | — | US | disclosed |
| EP-1148140-A1 | Process for the preparation of D-asparagine derivatives | Basilea Pharmaceutica AG (CH) | 2001-10-24 | — | — | EP | disclosed |