Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742003 | 1.00 | PSMB1 (0.56) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL7688519 | 0.92 | PSMB1 (0.57) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL5181237 | 0.89 | KYNU (0.60) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL7736831 | 0.89 | KYNU (0.60) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL28968911 | 0.89 | CASP1 (0.62) | CTSKCASP1 | |
| SCHEMBL6261373 | 0.89 | CASP1 (0.62) | CTSKCASP1 | |
| SCHEMBL8078067 | 0.88 | PSMB1 (0.56) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL7742013 | 0.88 | CTSL (0.55) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL7742011 | 0.88 | CTSL (0.55) | PSMB1CTSKPSMB8PSMB5CTSL | |
| SCHEMBL13439529 | 0.87 | SMN1; SMN2 (0.60) | CTSKCTSLCTSSCTSBMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420166-B2 | REACTING AN N-PROTECTED ASPARAGINE ESTER WITH A PROTEASE IN AQUEOUS SOLUTION AT PH OF 6.0 TO 7.5 AND AN ORGANIC SOLVENT, AND EXTRACTING THE N-PROTECTED-D-ASPARAGINE ESTER; CHEMICAL INTERMEDIATES TO ANTIBACTERIAL COMPOUNDS | BASOLEA PHARMACEUTICA AG (CH) | 2002-07-16 | — | — | US | disclosed |
| US-20010049127-A1 | Process for the preparation of D-asparagine derivatives | HOFFMANN-LA ROCHE INC. | 2001-12-06 | — | — | US | disclosed |
| EP-1148140-A1 | Process for the preparation of D-asparagine derivatives | Basilea Pharmaceutica AG (CH) | 2001-10-24 | — | — | EP | disclosed |