Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 6/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078067 | 0.93 | PSMB1 (0.56) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL7742845 | 0.92 | PSMB1 (0.56) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL7742003 | 0.92 | PSMB1 (0.56) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL7736831 | 0.92 | KYNU (0.60) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL5181237 | 0.92 | KYNU (0.60) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL1491365 | 0.91 | MME (0.62) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL722757 | 0.91 | MME (0.62) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL3569541 | 0.91 | MME (0.62) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL8955765 | 0.91 | CTSL (0.57) | PSMB1CASP1MMEECE1CTSK | |
| SCHEMBL4280674 | 0.88 | CASP1 (0.67) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017684-B1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1017684-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-12 | — | — | EP | disclosed |
| US-6083479-A | Contrast media for infarction and necrosis imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-04 | — | — | US | disclosed |
| WO-1999016757-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | disclosed |
| EP-0129163-B1 | ARPHAMENINE AND ITS RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0129163-A1 | Arphamenine and its related compounds, a process for their preparation and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1984-12-27 | — | — | EP | disclosed |