SCHEMBL5183115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6401065	0.83	CHRNA1 (0.39)	ALDH1A1HSD11B1DRD2CHRNB2SLC6A2
	SCHEMBL6400054	0.80	CHRNA1 (0.40)	ALDH1A1HSD11B1CHRNB2CHRNB4CHRNA3
	SCHEMBL7983386	0.75	ALDH1A1 (0.40)	ALDH1A1CYP1A2HCAR3HCAR2CYP2C9
	SCHEMBL4258794	0.70	CFTR (0.45)	ALDH1A1HCAR3HCAR2CYP2C9CYP2C19
	SCHEMBL5857767	0.67	MMP2 (0.41)	ALDH1A1CYP1A2HCAR3HCAR2CYP2C9
	SCHEMBL8149296	0.66	CYP1A2 (0.39)	ALDH1A1CYP1A2HCAR3HCAR2HSD11B1
	SCHEMBL10641405	0.66	CYP1A2 (0.39)	ALDH1A1CYP1A2HCAR3HCAR2MMP2
	SCHEMBL10641415	0.66	CYP1A2 (0.39)	ALDH1A1CYP1A2HCAR3HCAR2MMP2
	SCHEMBL10641412	0.66	CYP1A2 (0.39)	ALDH1A1CYP1A2HCAR3HCAR2MMP2
	SCHEMBL3291202	0.66	SIRT1 (0.46)	ALDH1A1CYP1A2HCAR3HCAR2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.