Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630335 | 0.78 | HPGD (0.38) | ELANEKIF11THRBKMT2AMEN1 | |
| SCHEMBL6629998 | 0.73 | MLYCD (0.58) | KMT2AALDH1A1RAB9AMLYCD | |
| SCHEMBL9542970 | 0.70 | ELANE (0.57) | ELANEKIF11KMT2AMEN1 | |
| SCHEMBL9566622 | 0.70 | ALDH1A1 (0.53) | KIF11THRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL630443 | 0.69 | ELANE (0.37) | ELANEKIF11THRBKMT2AMEN1 | |
| SCHEMBL1835776 | 0.67 | RAB9A (0.53) | ELANEKIF11THRBKMT2AMEN1 | |
| SCHEMBL4682259 | 0.66 | ELANE (0.53) | ELANEKIF11KMT2AMEN1ALDH1A1 | |
| SCHEMBL6284986 | 0.66 | KMT2A (0.64) | ELANEKIF11KMT2AMEN1ALDH1A1 | |
| SCHEMBL13650268 | 0.65 | MEN1 (0.48) | ELANEKIF11THRBKMT2AMEN1 | |
| SCHEMBL28096013 | 0.65 | F2 (0.54) | ELANEKIF11KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | disclosed |