Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350343 | 0.90 | DNM1 (0.42) | DNM1CA1CA2MGLLGGPS1 | |
| Sulfuric Acid SCHEMBL28610219 | 0.87 | SERPINE1 (0.37) | SERPINE1TP53DNM1CA1CA2 | |
| SCHEMBL10878157 | 0.82 | CA2 (0.35) | SERPINE1DNM1CA1CA2CES1 | |
| SCHEMBL10619703 | 0.82 | DNM1 (0.46) | DNM1CA1CA2MGLLGGPS1 | |
| Hydrochloric Acid SCHEMBL5604435 | 0.80 | DNM1 (0.48) | DNM1CA1CA2MGLLGGPS1 | |
| Hydrochloric Acid SCHEMBL4893505 | 0.80 | DNM1 (0.48) | DNM1CA1CA2MGLLGGPS1 | |
| Hydrochloric Acid SCHEMBL8461412 | 0.80 | DNM1 (0.48) | DNM1CA1CA2MGLLGGPS1 | |
| Hydrochloric Acid SCHEMBL1775317 | 0.80 | DNM1 (0.48) | DNM1CA1CA2MGLLGGPS1 | |
| Iodide SCHEMBL9575592 | 0.79 | EPHX2 (0.42) | TP53FAAH | |
| Acetic Acid SCHEMBL6729670 | 0.77 | GPR84 (0.40) | CES2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282520-B2 | External preparation | LION CORPORATION (JP) | 2007-10-16 | — | — | US | disclosed |
| EP-1437119-B1 | EXTERNAL PREPARATION CONTAIINING GALLIC ACID DERIVATIVES | LION CORP (JP) | 2007-08-15 | — | — | EP | disclosed |
| US-20040247551-A1 | External preparation | LION CORPORATION (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1437119-A1 | EXTERNAL PREPARATION | Lion Corporation (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247551-A1 | External preparation | GANAB, GANC, EEA1 | OPRM1 2428/4885SERPINE1 2824/4885TP53 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.