Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.36 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.36 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.36 |
| ▸ | S1PR2 known ✓ | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 known ✓ | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 known ✓ | Q9H228 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8461412 | 1.00 | DNM1 (0.48) | DNM1GBA1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL5604435 | 1.00 | DNM1 (0.48) | DNM1GBA1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4893505 | 1.00 | DNM1 (0.48) | DNM1GBA1CA12CA1CA2 | |
| SCHEMBL10619703 | 0.98 | DNM1 (0.46) | DNM1GBA1CA12CA1CA2 | |
| SCHEMBL8871571 | 0.89 | LMNA (0.48) | DNM1GBA1CA12CA1CA2 | |
| SCHEMBL9350343 | 0.88 | DNM1 (0.42) | DNM1GBA1CA12CA1CA2 | |
| Acetic Acid SCHEMBL6729670 | 0.87 | GPR84 (0.40) | TSHRPDE3AALDH1A1HSD17B10MEN1 | |
| SCHEMBL7759643 | 0.83 | DNM1 (0.46) | DNM1GBA1CA12CA1CA2 | |
| SCHEMBL7758120 | 0.83 | DNM1 (0.46) | DNM1GBA1CA12CA1CA2 | |
| SCHEMBL7754975 | 0.83 | DNM1 (0.46) | DNM1GBA1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12569426-B2 | Topical skin preparation composition | KAO CORPORATION (JP) | 2026-03-10 | — | — | US | disclosed |
| WO-2025033499-A1 | WATER-IN-OIL EMULSION COMPOSITION | 花王株式会社 | 2025-02-13 | — | — | WO | disclosed |
| US-20250009630-A1 | WATER-IN-OIL EMULSION COSMETIC | SHISEIDO COMPANY, LTD. (JP) | 2025-01-09 | — | — | US | disclosed |
| EP-4474019-A1 | WATER-IN-OIL EMULSION COSMETIC | Shiseido Company, Ltd. (JP) | 2024-12-11 | — | — | EP | disclosed |
| EP-4473956-A1 | WATER-IN-OIL EMULSION COSMETIC | Shiseido Company, Ltd. (JP) | 2024-12-11 | — | — | EP | disclosed |
| US-20240398683-A1 | WATER-IN-OIL EMULSION COSMETIC | SHISEIDO COMPANY, LTD. (JP) | 2024-12-05 | — | — | US | disclosed |
| US-12090218-B2 | Water-in-oil emulsion composition | SHISEIDO COMPANY, LTD. (JP) | 2024-09-17 | — | — | US | disclosed |
| CN-118555951-A | Water-in-oil type emulsified cosmetic | 株式会社资生堂 | 2024-08-27 | — | — | CN | disclosed |
| CN-118450883-A | Water-in-oil type emulsified cosmetic | 株式会社资生堂 | 2024-08-06 | — | — | CN | disclosed |
| US-20240225975-A9 | AN IMPROVED LONG WEARING SUNSCREEN COSMETIC | BASF SE (DE) | 2024-07-11 | — | — | US | disclosed |
| EP-1475070-A1 | WATER-IN-OIL EMULSION COMPOSITION AND EMULSION COSMETIC COMPRISING THE SAME | SHISEIDO COMPANY, LTD. (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6551770-B2 | For photomechanical process; support, a first layer of an organic silver salt, photosensitive silver halide and a reducing agent, and a second layer whose viscosity is higher at cooler temperatures than at warmer temperatures | KONICA CORPORATION (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20020018970-A1 | Heat developable photosensitive material | KONICA CORPORATION | 2002-02-14 | — | — | US | disclosed |
| EP-1168067-A2 | Heat developable photosensitive material | KONICA CORPORATION (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0765656-B1 | Water-in-oil type emulsion cosmetic composition | SHISEIDO CO LTD (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5853711-A | Water-in-oil emulsion cosmetic composition | SHISEIDO COMPANY, LTD (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0765656-A1 | Water-in-oil type emulsion cosmetic composition | SHISEIDO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0331833-B1 | WATER-IN-OIL EMULSION TYPE COSMETICS | SHISEIDO COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5015469-A | Water swellable clays, cationic surfactants, an alkoxy modified polysiloxane in water | SHIDEIDO COMPANY LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| EP-0331833-A1 | Water-in-oil emulsion type cosmetics | SHISEIDO COMPANY LIMITED (JP) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240398683-A1 | WATER-IN-OIL EMULSION COSMETIC | PRKAR2A, MC1R, CUTA | CA2 640/4885AGTR1 1316/4885OPRM1 3356/4885 |
| US-12090218-B2 | Water-in-oil emulsion composition | PHOSPHO1, ACTB, POLB | CA2 4738/4885AGTR1 4466/4885OPRM1 364/4885 |
| US-12569426-B2 | Topical skin preparation composition | KRT18, CUTA, TMSB10 | CA2 2663/4885AGTR1 2431/4885OPRM1 3396/4885 |
| US-20250009630-A1 | WATER-IN-OIL EMULSION COSMETIC | CUTA, LIPA, H1-0 | CA2 217/4885AGTR1 3998/4885OPRM1 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.