Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 8/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 8/20 | 0.53 |
| ▸ | CHRM2 known ✓ | P08172 | 6/20 | 0.53 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL3410520 | 0.80 | THRB (0.54) | CHRM1CHRM3CHRM4CHRM2THRB | |
| Hydrochloric Acid SCHEMBL28000634 | 0.78 | THRB (0.48) | CHRM1CHRM3CHRM4CHRM2THRB | |
| Benzophenone SCHEMBL1371756 | 0.78 | THRB (0.54) | CHRM1CHRM3CHRM4CHRM2THRB | |
| Hydrochloric Acid SCHEMBL134541 | 0.78 | CHRM5 (0.57) | CHRM1CHRM3CHRM4CHRM2THRB | |
| Hydrochloric Acid SCHEMBL28163699 | 0.77 | THRB (0.50) | CHRM1CHRM3CHRM4CHRM2THRB | |
| Acrylamide SCHEMBL11702078 | 0.77 | LMNA (0.37) | CHRM1CHRM3CHRM4CHRM2CYP2D6 | |
| SCHEMBL28033038 | 0.76 | THRB (0.49) | CHRM1CHRM3CHRM4CHRM2THRB | |
| Hydrochloric Acid SCHEMBL169126 | 0.76 | THRB (0.49) | CHRM1CHRM3CHRM4CHRM2THRB | |
| SCHEMBL25422044 | 0.76 | TSHR (0.56) | CHRM1CHRM3CHRM4CHRM2THRB | |
| SCHEMBL20908 | 0.76 | TSHR (0.56) | CHRM1CHRM3CHRM4CHRM2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190217311-A1 | CATIONIC POLYMER SELECTIVE DEPRESSANTS AND USE THEREOF IN MINERAL ORE PURIFICATION METHODS | KEMIRA OYJ (FI) | 2019-07-18 | — | — | US | claimed |
| US-11612898-B2 | Cationic polymer selective depressants and use thereof in mineral ore purification methods | KEMIRA OYJ (FI) | 2023-03-28 | — | — | US | disclosed |
| US-20190217311-A1 | CATIONIC POLYMER SELECTIVE DEPRESSANTS AND USE THEREOF IN MINERAL ORE PURIFICATION METHODS | KEMIRA OYJ (FI) | 2019-07-18 | — | — | US | disclosed |
| EP-1846477-B1 | POLYMER DISPERSION AND PROCESS FOR PREPARING A POLYMER DISPERSION | KEMIRA OYJ (FI) | 2016-03-09 | — | — | EP | disclosed |
| US-8299183-B2 | Polymer dispersion and process for preparing a polymer dispersion | AKZO NOBEL N.V. (NL) | 2012-10-30 | — | — | US | disclosed |
| EP-1846477-A1 | POLYMER DISPERSION AND PROCESS FOR PREPARING A POLYMER DISPERSION | Akzo Nobel N.V. (NL) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006071181-A1 | POLYMER DISPERSION AND PROCESS FOR PREPARING A POLYMER DISPERSION | AKZO NOBEL N.V. (NL) | 2006-07-06 | — | — | WO | disclosed |
| US-20060142464-A1 | Polymer dispersion and process for preparing a polymer dispersion | AKZO NOBEL N.V. (NL) | 2006-06-29 | — | — | US | disclosed |