Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 5/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709495 | 0.82 | THRB (0.60) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| SCHEMBL5184279 | 0.82 | CHRM1 (0.42) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| Hydrochloric Acid SCHEMBL2691425 | 0.82 | CHRM1 (0.42) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| SCHEMBL5070208 | 0.80 | THRB (0.54) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| SCHEMBL1047065 | 0.78 | THRB (0.55) | THRBCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL28000634 | 0.77 | THRB (0.48) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| SCHEMBL28054252 | 0.77 | THRB (0.54) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| Hydrochloric Acid SCHEMBL5183574 | 0.76 | CHRM1 (0.53) | THRBCHRM1CHRM3CHRM4CHRM2 | |
| SCHEMBL21837192 | 0.76 | CHRNB2 (0.68) | THRBCHRM1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1537495 | 0.75 | CHRNB2 (0.66) | THRBCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114134732-B | Compound thickener and preparation method thereof | 杭州传化精细化工有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118184880-A | Emulsion polymer stock solution and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-115353870-A | Self-degradation fracturing fluid thickening agent and preparation method thereof | 苏州石为开环保材料科技有限公司 | 2022-11-18 | — | — | CN | claimed |
| EP-2611528-A1 | FILTRATION MATERIAL FOR DESALINATION | Industrial Technology Research Institute (TW) | 2013-07-10 | — | — | EP | claimed |
| WO-2012028045-A1 | FILTRATION MATERIAL FOR DESALINATION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (CN) | 2012-03-08 | — | — | WO | claimed |
| US-20110210064-A1 | FILTRATION MATERIAL FOR DESALINATION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-09-01 | — | — | US | claimed |
| CN-118184880-A | Emulsion polymer stock solution and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115353870-B | Self-degrading fracturing fluid thickener and preparation method thereof | 苏州石为开环保材料科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-107353760-B | Polyacrylamide coating with super-hydrophilic property and preparation method and application thereof | 中国科学院理化技术研究所 | 2020-04-10 | — | — | CN | disclosed |
| CN-102380257-B | Desalination filter material | IND TECH RES INST | 2013-11-06 | — | — | CN | disclosed |
| US-8567611-B2 | Filtration material | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-29 | — | — | US | disclosed |
| EP-2611528-A1 | FILTRATION MATERIAL FOR DESALINATION | Industrial Technology Research Institute (TW) | 2013-07-10 | — | — | EP | disclosed |
| CN-102380257-A | Desalination filter material | IND TECH RES INST | 2012-03-21 | — | — | CN | disclosed |
| WO-2012028045-A1 | FILTRATION MATERIAL FOR DESALINATION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (CN) | 2012-03-08 | — | — | WO | disclosed |
| US-20110210064-A1 | FILTRATION MATERIAL FOR DESALINATION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-09-01 | — | — | US | disclosed |