Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182788 | 0.90 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL5183868 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL5183398 | 0.84 | MAPT (0.55) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL6847004 | 0.82 | HPD (0.46) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL5182941 | 0.80 | ALOX15 (0.37) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL5183669 | 0.78 | GLA (0.39) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL5183085 | 0.74 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL5182655 | 0.72 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL15033110 | 0.72 | CES2 (0.47) | ALDH1A1CYP1A2CYP2C19KDM4EPOLB | |
| SCHEMBL5182688 | 0.72 | MAPT (0.57) | ALDH1A1CYP1A2CYP2C19LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301492-B1 | NOVEL TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE KK (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-6770599-B2 | Tetrazole derivatives | BAYER CROPSCIENCE KK (JP) | 2004-08-03 | — | — | US | disclosed |
| US-20030224943-A1 | Novel tetrazole derivatives | BAYER CROPSCIENCE K. K. (JP) | 2003-12-04 | — | — | US | disclosed |
| EP-1301492-A1 | NOVEL TETRAZOLE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002002536-A1 | NOVEL TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE K.K. (DE) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224943-A1 | Novel tetrazole derivatives | CBR3, CBR1, ECH1 | ALDH1A1 783/4885CYP1A2 220/4885CYP2C19 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.