Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184742 | 0.94 | SIGMAR1 (0.49) | ADRA1ASIGMAR1KDM4ELMNAHTT | |
| SCHEMBL5183470 | 0.94 | SIGMAR1 (0.49) | ADRA1ASIGMAR1KDM4ELMNAHTT | |
| SCHEMBL4905532 | 0.94 | SIGMAR1 (0.49) | ADRA1ASIGMAR1KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL5186565 | 0.92 | HTT (0.49) | ADRA1ASIGMAR1KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL5186556 | 0.92 | HTT (0.49) | ADRA1ASIGMAR1KDM4ELMNAHTT | |
| Citric Acid SCHEMBL5185028 | 0.87 | KDM4E (0.48) | HTR1AADRA1DADRA1AADRA1BSIGMAR1 | |
| Dimethylamine SCHEMBL5941088 | 0.83 | HTT (0.41) | ADRA1ASIGMAR1KDM4ELMNAHTT | |
| SCHEMBL5184047 | 0.83 | HTR1A (0.43) | HTR1AADRA1DADRA1AADRA1BSIGMAR1 | |
| SCHEMBL19471239 | 0.82 | CHRNB2 (0.45) | SIGMAR1KDM4EHTTSLC6A4SLC6A3 | |
| SCHEMBL17847999 | 0.82 | LMNA (0.47) | ADRA1ASIGMAR1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784178-A1 | ARYL (OR HETEROARYL) AZOLYLCARBINOLS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-16 | — | — | EP | disclosed |
| US-20070021485-A1 | Aryl (or heteroaryl) azolylcarbinols | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-25 | — | — | US | disclosed |
| WO-2006010627-A1 | ARYL (OR HETEROARYL) AZOLYLCARBINOLS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021485-A1 | Aryl (or heteroaryl) azolylcarbinols | UGT2B17, ADH1B, GABBR1 | SLC6A4 1320/4885HTR1A 974/4885ADRA1D 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.