Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095842 | 0.93 | ALOX5 (0.39) | POLBL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL2524404 | 0.93 | ALOX5 (0.39) | POLBL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL6561059 | 0.90 | HTT (0.39) | KDM4EALDH1A1CHEK1HSD17B10HTT | |
| SCHEMBL9511404 | 0.89 | KDM4E (0.38) | L3MBTL1RECQLTDP1KDM4EALDH1A1 | |
| SCHEMBL5187338 | 0.88 | ALDH1A1 (0.41) | POLBL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL5577030 | 0.86 | HTT (0.36) | POLBTHRBKMT2AHSD17B10MEN1 | |
| SCHEMBL5576815 | 0.85 | TP53 (0.40) | POLBTHRBTDP1KDM4EGAA | |
| SCHEMBL2683123 | 0.84 | CHEK1 (0.31) | CHEK1KMT2AMEN1 | |
| SCHEMBL10341193 | 0.83 | CHEK1 (0.47) | CASP3KDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL2867820 | 0.83 | TAS1R3 (0.31) | KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319645-B1 | USEFUL IN ELECTROPHOTOGRAPHIC IMAGING AND PRINTING | XEROX CORPORATION | 2001-11-20 | — | — | US | claimed |
| EP-1235117-B1 | Imaging members | XEROX CORP (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1235117-A1 | Imaging members | Xerox Corporation (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6319645-B1 | USEFUL IN ELECTROPHOTOGRAPHIC IMAGING AND PRINTING | XEROX CORPORATION | 2001-11-20 | — | — | US | disclosed |