Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524404 | 0.89 | ALOX5 (0.39) | KDM4EMAPK1NPSR1ALDH1A1HPGD | |
| SCHEMBL1095842 | 0.89 | ALOX5 (0.39) | KDM4EMAPK1NPSR1ALDH1A1HPGD | |
| SCHEMBL5185602 | 0.89 | CASP3 (0.35) | KDM4EHSD17B10KMT2AMEN1MAPT | |
| SCHEMBL11153993 | 0.86 | KDM4E (0.47) | KDM4EHSD17B10KMT2AMAPK1MEN1 | |
| SCHEMBL6561059 | 0.86 | HTT (0.39) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5187338 | 0.84 | ALDH1A1 (0.41) | KDM4EKMT2AMEN1MAPTNPC1 | |
| SCHEMBL5577030 | 0.82 | HTT (0.36) | HSD17B10KMT2AMEN1MAPTNPC1 | |
| SCHEMBL5576815 | 0.82 | TP53 (0.40) | KDM4EKMT2AMEN1MAPTNPC1 | |
| SCHEMBL2683123 | 0.81 | CHEK1 (0.31) | KMT2AMEN1 | |
| SCHEMBL10341193 | 0.80 | CHEK1 (0.47) | KDM4EHSD17B10KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161648-B2 | Electrophotographic recording material | HOECHST AG (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0113437-B1 | ELECTROPHOTOGRAPHIC RECORDING MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | claimed |
| US-4668600-A | PHOTOCONDUCTIVITY, CARBONYL-CONTAINING BINDER | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-26 | — | — | US | claimed |
| US-4567125-A | CHARGE GENERATING AND TRANSPORT LAYERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-28 | — | — | US | claimed |
| EP-0182155-B1 | MULTI-ACTIVE PHOTOCONDUCTIVE INSULATING ELEMENTS EXHIBITING VERY HIGH ELECTROPHOTOGRAPHIC SPEED AND PANCHROMATIC SENSITIVITY AND METHOD FOR THEIR MANUFACTURE | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4618560-A | Multi-active photoconductive insulating elements exhibiting very high electrophotographic speed and panchromatic sensitivity and method for their manufacture | EASTMAN KODAK COMPANY (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0182155-A1 | Multi-active photoconductive insulating elements exhibiting very high electrophotographic speed and panchromatic sensitivity and method for their manufacture | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4578334-A | Multi-active photoconductive insulating elements and method for their manufacture | EASTMAN KODAK COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| US-4567125-A | CHARGE GENERATING AND TRANSPORT LAYERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-28 | — | — | US | disclosed |