Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982496 | 0.72 | GSK3B (0.45) | MAPK1ALDH1A1KDM4EGSK3BDAO | |
| SCHEMBL3411109 | 0.71 | POLB (0.44) | ALDH1A1KDM4EHTTHPGDPOLB | |
| SCHEMBL4777431 | 0.71 | MAOA (0.45) | ALDH1A1KDM4EGSK3BDAOKMT2A | |
| SCHEMBL3411071 | 0.70 | BCL2L1 (0.42) | ALDH1A1GAAGSK3BHPGDPOLB | |
| SCHEMBL11201725 | 0.67 | ALDH1A1 (0.59) | MAPK1ALDH1A1KDM4EGAAGSK3B | |
| SCHEMBL5765561 | 0.67 | CTNNB1 (0.34) | KDM4EGAAGSK3BSMN1; SMN2HTT | |
| SCHEMBL4711349 | 0.67 | KMT2A (0.33) | KMT2A | |
| Hydrochloric Acid SCHEMBL3507 | 0.67 | MAPK1 (0.59) | MAPK1ALDH1A1KDM4EGAAGSK3B | |
| SCHEMBL289811 | 0.66 | EGFR (0.50) | MAPK1ALDH1A1KDM4EKMT2AHTT | |
| SCHEMBL5489563 | 0.66 | HPGD (0.45) | ALDH1A1KDM4EGAAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799652-A1 | N-BENZENESULFONYL SUBSTITUTED ANILINO-PYRIMIDINE ANALOGS | Wyeth (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006044457-A1 | N-BENZENESULFONYL SUBSTITUTED ANILINO-PYRIMIDINE ANALOGS | WYETH (US) | 2006-04-27 | — | — | WO | disclosed |