Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190550 | 0.90 | ALDH1A1 (0.53) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5190305 | 0.82 | ALDH1A1 (0.54) | GAALMNAMEN1KMT2ATSHR | |
| SCHEMBL5192873 | 0.81 | LMNA (0.47) | GAALMNAMEN1KMT2AKDM4E | |
| SCHEMBL5191071 | 0.81 | LMNA (0.47) | GAALMNAMEN1KMT2A | |
| SCHEMBL5192029 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5192513 | 0.81 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5193168 | 0.79 | RAB9A (0.47) | GAALMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL5193999 | 0.79 | ALDH1A1 (0.46) | GAALMNAALDH1A1 | |
| SCHEMBL5193058 | 0.78 | KMT2A (0.45) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5190181 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |