Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805899 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2RIPK1LMNAL3MBTL1 | |
| SCHEMBL3122412 | 0.79 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL13895541 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2LMNATAAR1ALDH1A1 | |
| SCHEMBL1993383 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31675131 | 0.73 | RIPK1 (0.49) | GABRA1GABRB2RIPK1LMNATAAR1 | |
| SCHEMBL266645 | 0.73 | RIPK1 (0.49) | GABRA1GABRB2RIPK1LMNATAAR1 | |
| SCHEMBL9193804 | 0.72 | GABRA1 (0.52) | GABRA1GABRB2L3MBTL1TAAR1 | |
| SCHEMBL9190050 | 0.72 | GABRA1 (0.52) | GABRA1GABRB2L3MBTL1TAAR1 | |
| SCHEMBL29943841 | 0.72 | — | — | |
| SCHEMBL138361 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807394-A1 | PROCESS FOR THE SYNTHESIS OF 4-(3-SULFONYLPHENYL)-PIPERIDINES | Neurosearch Sweden AB (SE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006040156-A1 | PROCESS FOR THE SYNTHESIS OF 4-(3-SULFONYLPHENYL)-PIPERIDINES | NEUROSEARCH SWEDEN AB (SE) | 2006-04-20 | — | — | WO | disclosed |