Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210351 | 0.89 | FAAH (0.46) | MAPTLMNATP53CCR2KCNH2 | |
| SCHEMBL5192582 | 0.86 | FAAH (0.50) | MAPTLMNATP53CCR2KCNH2 | |
| SCHEMBL5191582 | 0.81 | TP53 (0.56) | MAPTLMNATP53CCR2KCNH2 | |
| SCHEMBL5193442 | 0.80 | MAPT (0.55) | MAPTCCR2MEN1KMT2ARAB9A | |
| SCHEMBL5193553 | 0.77 | PDGFRB (0.45) | PDGFRBSHMT2MAPTLMNATP53 | |
| SCHEMBL5199484 | 0.77 | MAPT (0.51) | MAPTMEN1KMT2A | |
| SCHEMBL5193943 | 0.77 | PDGFRB (0.44) | PDGFRBSHMT2MAPTLMNATP53 | |
| SCHEMBL5194086 | 0.76 | FAAH (0.62) | MAPTMEN1KMT2ARAB9A | |
| SCHEMBL5190802 | 0.74 | CCR2 (0.47) | PDGFRBMAPTLMNATP53CCR2 | |
| SCHEMBL5193973 | 0.72 | MAPT (0.47) | PDGFRBSHMT2MAPTL3MBTL1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |