Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822325 | 0.83 | OPRD1 (0.51) | SPHK2SPHK1OPRD1 | |
| SCHEMBL5193998 | 0.81 | TSHR (0.49) | TSHREPHX2SIGMAR1 | |
| SCHEMBL5191096 | 0.80 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2NPBWR1MCHR1 | |
| SCHEMBL5192834 | 0.80 | SPHK2 (0.47) | SPHK2SPHK1ALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL7814225 | 0.79 | NPBWR1 (0.58) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL7814221 | 0.79 | NPBWR1 (0.58) | KDM4EALDH1A1GAATSHRHTT | |
| SCHEMBL7309417 | 0.79 | SPHK1 (0.63) | KDM4ESPHK2SPHK1ALDH1A1GAA | |
| SCHEMBL8682776 | 0.78 | KDM4E (0.57) | KDM4ESPHK2SPHK1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7618359 | 0.78 | NPBWR1 (0.57) | KDM4EALDH1A1GAATSHRHTT | |
| Hydrochloric Acid SCHEMBL4616077 | 0.78 | FFAR1 (0.53) | TSHRHTTSMN1; SMN2KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |